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University of Michigan-developed PRIORI app to get first test in patients outside Michigan

$2.9 million grant supports study of suicide risk assessment

February 07, 2017

A multidisciplinary team from Care New England's Butler Hospital, Brown University and the University of Michigan has come together to advance screening capabilities for suicide risk. The group received a $2.9 million grant from the National Institute of Mental Health to conduct a five-year research study utilizing innovative smartphone technology. Using the smartphone app PRIORI (Predicting Individual Outcomes for Rapid Intervention) designed by the Prechter bipolar research team at the University of Michigan, researchers will record and analyze changes in speech patterns to identify how they relate to changes in suicide risk.

The tenth leading cause of death in the United States, suicide is responsible for 42,000 deaths in the country each year. Although there are many known risk factors for suicide, the majority of individuals who have these risk factors do not go on to attempt suicide – pointing to the importance of identifying new strategic risk factors for suicidal thoughts and behaviors.

"It is our hope that results of this study will have implications for both prevention and early intervention of suicide, and that the smartphone technology will provide methods for monitoring patients' suicide risk over time," said Heather Schatten, Ph.D., a research psychologist at Butler Hospital and assistant professor of research at The Warren Alpert Medical School of Brown University. One of three principal investigators for the study, Dr. Schatten is joined by a multidisciplinary team that includes research psychologists, psychiatrists, computer scientists and engineers, and a quantitative scientist.

"We are very pleased to welcome this first test of our app outside of Michigan and in a patient population with diverse diagnoses," says Melvin McInnis, M.D., a professor of psychiatry at the U-M Medical School who leads the U-M team that developed the program with funding from the Heinz C. Prechter Bipolar Research Fund and the Richard Tam Foundation. McInnis is a member of the U-M Depression Center, part of Michigan Medicine, the U-M academic medical center. McInnis collaborates on the PRIORI project with Emily Mower Provost, Ph.D., a U-M assistant professor of electrical engineering and computer science who is the principal investigator for the Michigan site. "Our initial testing with people who have bipolar disorder continues, and we look forward to the results of both studies," says Dr. Mower Provost.

Participants in the study will be recruited in a psychiatric inpatient setting, an important population given the elevated suicide rates in the weeks and months following hospital discharge. The study begins recruitment this month.

About Michigan Medicine
Michigan Medicine is a national leader in advanced patient care, innovative research to improve human health and comprehensive education of physicians, health professionals and medical scientists. Michigan Medicine includes a 1,000-bed hospital complex and more than 40 clinical care locations, and the U-M Medical School with its 1,900-physician faculty group practice, numerous research laboratories and projects funded by more than $470 million in research grants, and highly regarded training programs. Michigan Medicine has earned recognition for quality and safety from U.S. News & World Report, the Leapfrog Group and beyond. More information at www.uofmhealth.org.

About Butler Hospital
Butler Hospital, a member of Care New England, is the only private, nonprofit psychiatric and substance abuse hospital serving adults, seniors and adolescents in Rhode Island and southeastern New England. Founded in 1844, it was the first hospital in Rhode Island and has earned a reputation as the leading provider of innovative psychiatric treatments in the region. The major affiliated teaching hospital for psychiatry and behavioral health at The Warren Alpert Medical School of Brown University, Butler is recognized worldwide as a pioneer in conducting cutting-edge research.